Alessio Fasano, PhD
Massachusetts General Hospital
Dr. Fasano also directs the Mucosal Immunology and Biology Research Center and is associate chief for Basic, Clinical and Translational Research. Under his leadership, investigators are studying the molecular mechanisms of autoimmune disorders including celiac disease, and other-gluten-related disorders. He has been named visiting professor of pediatrics at Harvard Medical School. He authored the groundbreaking study in 2003 that established the rate of celiac disease at one in 133 Americans. Widely sought after by national and international media, Dr. Fasano has been featured in hundreds of interviews including outlets such as The New York Times, The Wall Street Journal; National Public Radio; CNN; Bloomberg News, and others.
BRAIN Funded Projects
Using a Humanized Mouse Model And Human Intestinal Tissue to Evaluate the Zonulin Pathway For Personalized Treatment of Autism (2021)
The project to identify biomarkers to stratify the ASD population in specific subgroups and to validate the zonulin inhibitor AT1001 (already showing robust safety profiles in phase 3 human trials) as a possible personalized therapeutic strategic treatment.
Recent & Selected Publications
Fasano A, Sapone A, Zevallos V, Schuppan D. Nonceliac gluten sensitivity. Gastroenterology. 2015;148(6):1195-1204. doi:10.1053/j.gastro.2014.12.049
BRAIN Synchrony Symposia presentations
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